Unfortunately, voicing frustrations to colleagues can be just as futile, and prompt the short and not so sweet response: “That’s science”. To be sure, cultivating a career in the frighteningly competitive world of research leaves no room for hand-holding or mollycoddling, and I truly believe that principal investigators need full-body elephant-hide transplants to achieve the thick skin required for the job. However, we are all human and everyone needs some sort of coping mechanism. Losing this mechanism is always a disaster.
Extract from an article by Lydia Soraya Murray, on disappointments in the lab.